Inhibitory activity of Mentha spicata oils on biofilms of Proteus mirabilis isolated from burns

Introduction and Aim: Proteus mirabilis is an opportunistic pathogen, infecting humans, through the release of endotoxins enzymes such as urease, hemolysin, protease, DNase etc. One factors contributing to its virulence unusual ability form crystalline biofilms. This study aimed investigate effect Mentha spicata volatile oil on P. biofilm formation. Materials Methods: was isolated from infected wound burns patients using conventional biochemical tests. Vitek 2-Compact System used confirm diagnosis bacterial isolates. The isolates were tested for their susceptibility 11 antibiotics. Aqueous alcoholic extracts well Volatile Oil natural Menthol extracted M. inhibit formation by mirabilis. Results: In this 16 out 45 burn injury samples positive Bacterial found be resistant drugs Levofloxacin Norfloxacin, with percentages 10.2% 11.8%, respectively. Majority these had capacity produce several factors, including in variable amounts DNase, gelatinase. component menthol inhibited at increasing concentrations. Conclusion: compound are effective inhibiting